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abbit Anti –c-Met/HGFR
  • 發(fā)布日期:2009-10-28      瀏覽次數(shù):1277
    •  abbit Anti –c-Met/HGFR

                         (hepatocyte growth factor receptor)

       

       

      Quantity size :   0.1ml  (Reconstitued with 200ul pH 7.4  0.01 M PBS or diluent of antibody)

       

      Background:   c-Met (met proto-oncogene) (hepatocyte growth factor receptor), isoform ; CRA_b; (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) receptor protein tyrosine kinase. The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for c-met is hepatocyte growth factor/scatter factor (HGF/SF) and while normal HGF/SF-Met signaling is required for embryonic development, abnormal c-met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.

       

       Specificity :    · anti- c-Met is a rabbit polyclonal antibody unconjugated

                      · specific for c-Met of human dog, rat and mouse

                      · epitope mapping in the N-terminus of c-Met of human dog, rat and mouse

      · use for western blotting, elisa, immunoprecipitation

                         and immunohistochemistry

      · Protein G affinity chromatography purification, purity :>95%

      · Isotype: IgG

      · mol wt: 142kDa

       

      Application:     · WB1200-500

      · ELISA1500-1000

      · IHC 1200-500

      · Optimal working dilutions must be determined by the end user.

                      

      Storage:        Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4  0.01 M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ºC.

       

      Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

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